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Isaac Scientific Publishing
Journal of Advances in Molecular Biology
Prof. Fakhrul Islam,  Jazan University, Saudi Arabia
Department of Pharmacology and Toxicology,
Faculty of Pharmacy, Jazan University,
Jazan, Kingdom of Saudi Arabia
Research Interests
Selected Publication List
•Ejaz Ahmed M, Khan MM, Javed H, Vaibhav K, Khan A, Tabassum R, Ashafaq M, Islam F, Safhi MM, Islam F. Amelioration of cognitive impairment and neurodegeneration by catechin hydrate in rat model of streptozotocin-induced experimental dementia of Alzheimer's type. Neurochem Int. 2013 Feb 11; 62(4):492-501.
•Ahmad ME, Hayate Javed, , Khan MM, Vaibhav K, Ahmad A, Khan A, Tabassum R, Islam F, Safhi MM, Islam F. Effects of Withania somnifera on cognitive deficits and oxidative damage induced by intracerebroventricular injection of streptozotocin in rats. Protoplasm 2013, DOI 10.1007?s00709-013-0482-2.
•Tabassum R, Vaibhav K, Shrivastava P, Khan A, Ahmad ME, Javed H, Islam F, Ahmad S, Siddiqui MS, Safhi MM, Islam F. Centella asiatica attenuates the neurobehavioral, neurochemical and histological changes in transient focal middle cerebral artery occlusion rats. Neurol. Sci 2013, DOI:10.1007/s10072-012-1163-1.
•Shrivastava P, Vaibhav K, Tabassum R, Khan A, Ishrat T, Khan MM, Ahmad A, Islam F, Safhi MM, Islam F. Anti-apoptotic and inflammatory effect of piperine on 6-OHDA induced Parkinson’s rat model. J. Neutritional Biochem. 2012.
•Khan A, Vaibhav K, Javed H, Khan MM, Tabassum R, Ahmed ME, Srivastava P, Gulrana Khuwaja G, Islam F, Siddiqui MS, Safhi MM, Islam F. Attenuation of Ab-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress. Mol Cell Biochem (2012) 369:55–65
•Vaibhav K, Shrivastava P, Khan A, Javed H, Tabassum R, Ahmed ME, Khan MB, Moshahid Khan M, Islam F, Ahmad S, Siddiqui MS, Safhi MM, Islam F. Azadirachta indica mitigates behavioral impairments, oxidative damage, histological alterations and apoptosis in focal cerebral ischemia-reperfusion model of rats. Neurol Sci. 2012 Nov 28. [Epub ahead of print]
•Khan MB, Khan MM, Khan A, Ahmed ME, Ishrat T, Tabassum R, Vaibhav K, Ahmad A, Islam F. Naringenin ameliorates Alzheimer's disease (AD)-type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular-streptozotocin in rat model. Neurochem Int. 2012 Dec; 61(7):1081-93.
•Raza SS, Khan MM, Ahmad A, Ashafaq M, Wagner AP, Safhi MM, Islam F. Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental stroke. Neuroscience. 2013; 230:157-171.
•Alam S, Khan ZI, Mustafa G, Kumar M, Islam F, Bhatnagar A, Ahmad FJ. Development and evaluation of thymoquinone-encapsulated chitosan nanoparticles for nose-to-brain targeting: a pharmacoscintigraphic study. Int J Nanomedicine. 2012; 7: 5705-18.
• Ashafaq M, Raza SS, Khan MM, Ahmad A, Javed H, Ahmad ME, Tabassum R, Islam F, Siddiqui MS, Safhi MM, Islam F. Catechin hydrate ameliorates redox imbalance and limits inflammatory response in focal cerebral ischemia. Neurochem. Res. 2012, Aug; 37(8): 1747-60.
•Vaibhav K, Shrivastava P, Javed H, Khan A, Tabassum R, Ejaz Ahmed ME, Mohd. Moshahid Khan MM, Farah Islam F, M. Saeed Siddiqui MS, Mohammed M. Safhi MM and Fakhrul Islam F. Piperine suppresses cerebral ischemic reperfusion-induced inflammation through the repression of COX-2, NOS-2 and NF-κB in middle cerebral artery occlusion rat model. Mol. Cell Biochem. 2012, Aug; 367(1-2): 73-84.
•Javed H, Khan MM, Ahmad A, Vaibhav K, Ahmad ME, Khan A, Ashafaq M, Islam F, Siddiqui MS, Safhi MM, Islam F. Rutin prevents cognitive impairments by ameliorating oxidative stress and neuro-inflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience. 2012, May 17; 210:340-52.
•Ansari RW, Shukla RK, Yadav RS, Seth K, Pant AB, Singh D, Agrawal AK, Islam F, Khanna VK. Involvement of dopaminergic and serotonergic systems in the neurobehavioral toxicity of lambda-cyhalothrin in developing rats. Toxicol Lett. 2012 Feb 24; 211(1):1-9.
•Ansari RW, Shukla RK, Yadav RS, Seth K, Pant AB, Singh D, Agrawal AK, Islam F, Khanna VK. Cholinergic Dysfunctions and Enhanced Oxidative Stress in the Neurobehavioral Toxicity of Lambda-Cyhalothrin in Developing Rats. Neurotox Res. 2012, Nov; 22(4):292-309.
• Ashafaq M, Khan MM, Shadab Raza S, Ahmad A, Khuwaja G, Javed H, Khan A, Islam F, Siddiqui MS, Safhi MM, Islam F. S-allyl cysteine mitigates oxidative damage and improves neurologic deficit in a rat model of focal cerebral ischemia. Nutr Res. 2012 Feb; 32(2):133-43.
•Ahmad A, Khan MM, Raza SS, Javed H, Islam F, ed M. Safhi MM and Islam F. Ocimum sanctum attenuates oxidative damage and neurological deficits following focal cerebral ischemia/reperfusion injury in rats. Neurological Science 2012 Dec; 33(6):1239-47.
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