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Isaac Scientific Publishing
Journal of Advances in Molecular Biology
Prof. Jianyong Li,  Department of Biochemistry at the Virginia Tech, USA
Biochemistry, Virginia Tech
111 Engel Hall, Blacksburg, VA 24061
Research Interests
Insect Biochemistry, peptide mass spectrometry, protein structure and function.
Selected Publication List
•Han Q et al. (2015) crystal structure of the complex between AvrRxo1-ORF1, a type III effector and its cognate chaperon, AvrRxo1-ORF2. Structure 23: 1900-1909.
•Verma A, Wong DM, Islam R, Tong F, Ghavami M, Mutunga JM, Slebodnick C, Li J, Viayna E, Lam PC, Totrov MM, Bloomquist JR, Carlier PR (2015) 3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae. Bioorg Med Chem 23: 1321-1340.
•Pinto JT, Krasnikov BF, Alcutt S, Jones ME, Dorai T, Villar MT, Artigues A, Li J, Cooper AJ (2014). Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine. J Biol Chem 289: 30950-30961.
•Torrens-Spence MP, Lazear M, von Guggenberg R, Ding H and Li J (2014) Investigation of a substrate-specifying residue within Papaver somniferum and Catharanthus roseus aromatic amino acid decarboxylases. Phytochemistry 106: 37-43.
•Li M, Liu P, Wiley JD, Ojani R, Bevan DR, Li J, Zhu J (2014) A steroid receptor coactivator acts as the DNA-binding partner of the methoprene-tolerant protein in regulating juvenile hormone response genes. Mol Cell Endocrinol 394: 47-58.
•Lu MX, Cao SS, Du YZ, Liu ZX, Liu P, and Li J (2013) Diapause, signal and molecular characteristics of overwintering Chilo suppressalis (Insecta: Lepidoptera: Pyralidae). Sci Rep 3: 3211.
•Vavricka CJ, Han Q, Mehere P, Ding H, Christensen BM and Li J (2014) Tyrosine metabolic enzymes from insects and mammals: a comparative perspective. Insect Sci 21: 13-19
•Lu MX, Du YZ, Cao SS, Liu P, Li J (2013) Molecular Cloning and Characterization of the First Caspase in the Striped Stem Borer, Chilo suppressalis. Int J Mol Sci 14: 10229-10241.
•Miao J, Fan Q, Parker D, Li X, Li J, Cui L (2013) Puf mediates translation repression of transmission-blocking vaccine candidates in malaria parasites. PLoS Pathog 9: e1003268.
•You C, Chen H, Myung S, Sathitsuksanoh N, Ma H, Zhang XZ, Li J, Zhang YH (2013) Enzymatic transformation of nonfood biomass to starch. Proc Natl Acad Sci USA 110: 7182-7187.
•Torrens-Spence MP, von Guggenberg R, Lazear M, Ding H, Li J (2014) Diverse functional evolution of serine decarboxylases: identification of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates. BMC Plant Biol 14: 247
•Torrens-Spence MP, Liu P, Ding H, Harich K, Gillaspy G and Li J (2013) Biochemical evaluation of the decarboxylation and decarboxylation-deamination activities of plant aromatic amino acid decarboxylases. Journal of Biological Chemistry 288: 2376-2387.
•Wong DM, Li J, Lam PC, Hartsel JA, Mutunga JM, Totrov M, Bloomquist JR and Carlier PR (2013) Aryl methylcarbamates: Potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae. Chemico-Biological interaction 203: 314-318.
•Liu P, Ge X, Ding H, Jiang H, Christensen BM and Li J (2012) Role of glutamate decarboxylase-like protein 1 (GADL1) in taurine biosynthesis Journal of Biological Chemistry 287: 40898-40906.
•Han Q, Robinson H, Ding H, Christensen BM and Li J (2012) Evolution of insect arylalkylamine N-acetyltransferases: structural evidence from the yellow fever mosquito, Aedes aegypti. Proceedings of the National Academy of Sciences 109: 11669-11674.
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