Annals of Advanced Agricultural Sciences
GC/MS Analysis of Gossypitrin Sample with Antioxidant and Neuroprotective Effects against Chemical Hypoxia-Induced PC12 Cell Death
Download PDF (395.2 KB) PP. 37 - 44 Pub. Date: August 1, 2018
Author(s)
- José González*
Departamento de Farmacia, Instituto de Farmacia y Alimentos, Universidad de La Habana, Calle 222, # 231 e/23 y 31, La Coronela, La Lisa, CP 13600, La Habana, Cuba - María A. Bécquer-Viart
Instituto de Farmacia y Alimentos, Universidad de La Habana, Calle 222, # 2317 e/23 y 31, La Coronela, La Lisa, CP 13600, La Habana, Cuba - Armando Cuéllar
Departamento de Farmacia, Instituto de Farmacia y Alimentos, Universidad de La Habana, Calle 222, # 231 e/23 y 31, La Coronela, La Lisa, CP 13600, La Habana, Cuba - Julio Pérez
Centro Nacional de Toxicología, Hospital Militar "Carlos J. Finlay", Calle 114 y 31, Marianao, CP 11500, La Habana, Cuba - Max Monan
Association pour la Recherche sur la Valorisation des Ressources Naturelles de la Martinique (ARVARNAM), 16 lot. les Rosiers, Quartier Thoraille, 97215, Rivière-Salée, Martinique, France
Abstract
Keywords
References
[1] Allen CL, Bayraktutan U (2009) Oxidative stress and its role in the pathogenesis of ischemic stroke. Int J Stroke 4: 461–470.
[2] Alonso-Alconada D, Alvarez A, Arteaga O, Martínez-Ibargüen A, Hilario E (2013). Neuroprotective effect of melatonin: a novel therapy against perinatal hypoxia ischemia. Int J Mol Sci 14: 9379–9395.
[3] Bécquer-Viart MA, González-Yaque J, Fonseca-Fonseca LA, Nú?ez-Figueredo Y, Pardo Andreu GL. (2018). Antioxidant and neuroprotective effects of gossypitrin, a flavonoid from Talipariti elatum, against chemical hypoxia-induced PC12 cell death. J Pharm Pharmacogn Res 6(2): 72–80.
[4] Commenges D., V. Scotet, S. Renaud, H. Jacqmin-Gadda, P. Barberger-Gateau, and J. F. Dartigues. (2000). “Intake of flavonoids and risk of dementia”. The European Journal of Epidemiology, vol.16, no. 4, pp. 357–363.
[5] Erdogdu, Y.; Unsalan, O.; Sajan, D. & Gulluoglu, M.T. (2010). Structural conformations and vibrational spectral study of chloroflavone with density functional theoretical simulations. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 76, 2, 130-136.
[6] Fraga, C.G.; Galleano, M.; Verstraeten, S.V. & Oteiza, P.I. (2010). Basic biochemical mechanisms behind the health benefits of polyphenols. Molecular Aspects of Medicine, 31, 6, 435-445.
[7] Gomes, A.; Fernandes, E.; Lima, J.L.F.C.; Mira, L. & Corvo, M.L. (2008) Molecular Mechanisms of Anti-Inflammatory Activity Mediated by Flavonoids, Current Medicinal Chemistry, 15, 1586-1605.
[8] González J., Cuéllar A., Abreu P., Monan M., Nossin E., and Fran?ois-Haugrin F. (2017). Antioxidant Activity of gossypitrin isolated from the petals of Talipariti elatum (Sw.) Fryxell (Malvaceae) in Cuba. International Journal of Engineering Research & Science (IJOER). Vol-3, Issue-10, October- 2017, pp. 17-22.
[9] González J., Cuéllar A., Gómez E., Dopico E., Vázquez R., de Armas T. (2017). EVALUACIóN FARMACOGNóSTICA Y FITOQUíMICA PRELIMINAR DE LOS PISTILOS CON POLEN, LA CORTEZA Y LA MADERA DE TALIPARITI ELATUM SW. Revista de Ciencias Farmacéuticas y Alimentarias. Vol.3 / No.2. pp. 1-6. ISSN: 2411-927X / RNPS: 2396
[10] González J., Cuéllar A., Nossin E., & Max Monan M. (2017). Iron Chelating Activity of Gossypitrin Isolated from the Petals of Talipariti elatum Sw. (Fryxell) Malvaceae. Journal of Agricultural Studies. Vol. 5, No. 2. Pp. 1-12. ISSN 2166-0379
[11] González J., Romero J. A., Cuéllar A., Monan M., Nossin E., and Fran?ois-Haugrin F. (2016). HPLC Analysis of the Total Extract and Gossypitrin Isolated from the Petals of Talipariti elatum (S.w) Fryxell (Malvaceae). Int.J.Curr.Res.Aca.Rev.4 (7): 89-95. doi: http://dx.doi.org/10.20546/ijcrar.2016.407.011
[12] Kumar S. and Abhay K. Pandey. (2013). Chemistry and Biological Activities of Flavonoids: An Overview. Hindawi Publishing Corporation. The Scientific World Journal. Volume 2013, Article ID 162750, 16 pages http://dx.doi.org/10.1155/2013/162750
[13] Li, X.-H., Liu, X.-R.; Zhang, X.-Z. 2011. Molecular structure and vibrational spectra of three substituted 4-thioflavones by density functional theory and ab initio Hartree-Fock calculations. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 78, 1, 528-536.
[14] Lu, Y., Yu, K., Qu, H.B., Cheng, Y.Y. 2007. Development of an HPLC-UV-ELSD method for quantification of multiple components of a Chinese medicine made from radix Salvia miltiorrhiza and Panax notoginseng. Chromatographia, 65: 19-24.
[15] Manzanero S, Santro T, Arumugam TV. (2013). Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury. Neurochem Int 62: 712–718.
[16] Panickar KS, Jang S (2013). Dietary and plant polyphenols exert neuroprotective effects and improve cognitive function in cerebral ischemia. Recent Pat Food Nutr Agric 5: 128–143.
[17] Pérez-Hernández J, Zaldívar-Machorro VJ, Villanueva-Porras D, Vega-ávila E, Chavarría A (2016). A potential alternative against neurodegenerative diseases: Phytodrugs. Oxid Med Cell Longev 2016: 8378613.
[18] Pinheiro P. F and Justino G. C. (2012). Structural Analysis of Flavonoids and Related Compounds – A Review of Spectroscopic Applications. Phytochemicals – A Global Perspective of Their Role in Nutrition and Health. Edited by Dr Venketeshwer Rao. Pp. 33-56. ISBN: 978-953-51-0296-0, InTech.
[19] Ren Y, Wei B, Song X, An N, Zhou Y, Jin X, Zhang Y. (2015.) Edaravone's free radical scavenging mechanisms of neuroprotection against cerebral ischemia: review of the literature. Int J Neurosci 125: 555–565.
[20] Rohloff J. (2015). Analysis of Phenolic and Cyclic Compounds in Plants Using Derivatization Techniques in Combination with GC-MS-Based Metabolite Profiling. Molecules, 20, 3431-3462; doi:10.3390/molecules20023431
[21] Soledispa P. A., González J., Cuéllar A., Pérez J., Monan M. (2018). GC-MS Chemical Characterization of Main Components of Smilax Domingensis Wild. in Cuba. Journal of Agricultural Studies. Vol. 6, No. 2. 79-86. ISSN 2166-0379
[22] Spencer, J.P. (2010). The impact of fruit flavonoids on memory and cognition. British Journal of Nutrition, 31, 6, 546-557.
[23] Spencer, J.P.; Vauzour, D. & Rendeiro, C. (2009). Flavonoids and cognition: the molecular mechanisms underlying their behavioral effects. Archives of Biochemistry and Biophyics, 492, 1-2, 1-9.
[24] Yaque, J.G., Cuéllar, A., Massi, L., Monan, M., Nossin, E. and Fran?ois-Haugrin, F. (2016). Isolation and Characterization of Flavonols by HPLC-UV-ESI-MS/MS from Talipariti elatum S.w. American Journal of Plant Sciences, 7, 1198-1204.