Isaac Scientific Publishing

Annals of Advanced Agricultural Sciences

GC/MS Analysis of Gossypitrin Sample with Antioxidant and Neuroprotective Effects against Chemical Hypoxia-Induced PC12 Cell Death

Download PDF (395.2 KB) PP. 37 - 44 Pub. Date: August 1, 2018

DOI: 10.22606/as.2018.23002

Author(s)

  • José González*
    Departamento de Farmacia, Instituto de Farmacia y Alimentos, Universidad de La Habana, Calle 222, # 231 e/23 y 31, La Coronela, La Lisa, CP 13600, La Habana, Cuba
  • María A. Bécquer-Viart
    Instituto de Farmacia y Alimentos, Universidad de La Habana, Calle 222, # 2317 e/23 y 31, La Coronela, La Lisa, CP 13600, La Habana, Cuba
  • Armando Cuéllar
    Departamento de Farmacia, Instituto de Farmacia y Alimentos, Universidad de La Habana, Calle 222, # 231 e/23 y 31, La Coronela, La Lisa, CP 13600, La Habana, Cuba
  • Julio Pérez
    Centro Nacional de Toxicología, Hospital Militar "Carlos J. Finlay", Calle 114 y 31, Marianao, CP 11500, La Habana, Cuba
  • Max Monan
    Association pour la Recherche sur la Valorisation des Ressources Naturelles de la Martinique (ARVARNAM), 16 lot. les Rosiers, Quartier Thoraille, 97215, Rivière-Salée, Martinique, France

Abstract

Gossypitrin, a natural occurring flavonoid and the main bioactive substance from the flowers of Talipariti elatum Sw. (Blue Mahoe), is traditionally used in Cuba as expectorant and antasthmatic. It was analyzed by GC/MS using BSTFA as derivatization agent to get information about the chemical components present in the sample. Gas Chromatography Mass Spectrometry (GC-MS) analysis revealed the presence of another five different chemical compounds. According to NIST21 and NIST107 Libraries Databases the phytocompounds screened were D-Turanose, Thymol-β-d-glucopyranoside, Ribitol, 2-Deoxy ribose and Hydroquinone-β-d-glucopyranoside. In addition, the structures of another 13 compounds have been identified by GC/MS experiments after isolation in T. elatum in this sample for the first time.

Keywords

Gossypitrin, Talipariti elatum, GC/MS, chemical components, flavonoid.

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