Isaac Scientific Publishing

Modern Organic Chemistry Research

Synthesis of Some New Fluorinated Fused Heteropolycyclic Nitrogen Systems Containing pyrazolo[3,4-d]pyrimidines Moiety and Their Effects on Cellobiase Activity Produced by Aspergillus nidulans Fungi

Download PDF (329.1 KB) PP. 172 - 178 Pub. Date: November 1, 2017

DOI: 10.22606/mocr.2017.24003

Author(s)

  • Dina A. Bakhotmah*
    King abdul aziz uneversity, colleg of Scinece, chemistry departmaent, jeddah, Saudi Arabia
  • Reda M. Abdel-Rahman

    King abdul aziz uneversity, colleg of Scinece, chemistry departmaent, jeddah, Saudi Arabia
  • Montha fakhrji

    King abdul aziz uneversity, colleg of Scinece, chemistry departmaent, jeddah, Saudi Arabia
  • Abrar kamal

    King abdul aziz uneversity hospital, Jeddah, Saudi Arabia

Abstract

New Fluorinated fused heteropolycyclic nitrogen systems containing pyrazolo[3,4-d] pyrimidines moieties have been synthesized from the ring closure reaction of the corresponding hydrazine derivatives with bifunctional compounds. Structure of the new fluorinated systems obtained has been established from elemental and spectral analysis. The effect of these compounds was evaluated on the activity of cellobiase produced by Aspergillus nidulans fungi.

Keywords

Pyrimidines, fluoropyrazol, cellobiase activity, hydrazine derivatives.

References

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